Human Vascular Smooth Muscle Cell Line

Sci rep 6 23596 2016. Human vascular smooth muscle cells vsmcs in culture are an important tool in understanding how vsmcs function and contribute to vessel wall contraction as well as disease. Primary human aortic smooth muscle cells haosmc are isolated from plaque free regions of the human aorta and stain positive for smooth muscle α actin.

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Human vascular smooth muscle cell line.

Each cell line was. The in vitro generation of human vascular cells e g. Blood brain barrier damage vatine et al 2019. Smooth muscle cells play a critical role in cardiac and vascular diseases including stroke and atherosclerosis.

Warm both the trypsin edta for primary cells atcc pcs 999 003 and the trypsin neutralizing solution atcc pcs 999 004 to room temperature prior to dissociation. Pulmonary artery smooth muscle cells atcc offers a wide array of products for the culture of smooth muscle cells including media and supplements that will support the propagation of smooth muscle cells under low serum cell culture conditions. Monday friday 8am 5pm pacific standard time. The present study was designed to investigate the effect of the tumor microenvironment on vascular smooth muscle cells vsmcs.

Uterine smooth muscle cells atcc offers primary smooth muscle cells derived from the uterus. Smooth muscle cells smcs vascular endothelial cells vecs represents a promising approach to regenerate compromised vascular beds leeper et al 2010 as well as to model specific features of vascular dysfunction e g. Passage normal vascular smooth muscle cells when culture has reached approximately 80 confluence. Salusin β induces foam cell formation and monocyte adhesion in human vascular smooth muscle cells via mir155 nox2 nfκb pathway.

Vascular smooth muscle cells line the vessel walls of large and small arteries arterioles and veins. We used the tumor conditioned medium tcm from human crc cell line ht29 cells to mimic tumor microenvironment and examined its effect on the proliferation and apoptosis of vsmcs in vitro. The pulsatile pressure produced by the heart causes a cyclic distention of the aorta. The smooth muscle cells in the aortic wall subsequently contract it again.

Human brain vascular smooth muscle cells. A wide variety of primary smooth muscle cells from different tissues species and vascular bed smooth muscle are offered. All smooth muscle cells are high purity low passage.

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